Gene genies: CRISPR’s critical moment

Negotiations in Turkey to bring peace to Ukraine could be a flop. But the repercussions of shifting alliances with Russia will play out in this weekend’s presidential election in Romania where the leading candidates have polarised opinion. Why British towns are shabby and disorderly (10:48). And the brilliance of women’s basketball in America (18:30). Listen to what matters most, from global politics and business to science and technology—Subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

Drugs in America often cost more than three times as much as those elsewhere. But Donald Trump’s plan to cut prescription costs and impose tariffs may have unintended consequences for consumers. Inside North Korea’s crypto-heist: from hermit kingdom to hacking kingdom (10:45). And remembering Alvaro Mangino, who survived the 1972 Andes air crash (18:39). Listen to what matters most, from global politics and business to science and technology—Subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

As Donald Trump removes bans on trade with Syria and meets its leader Ahmed al-Sharaa, our correspondent analyses the implications. Two feuding political dynasties in the Philippines use mid-term elections as a proxy battle (10:03). And introducing V-Tubers, creators behind live-streams of cartoon avatars coming to a screen near you (18:42). Listen to what matters most, from global politics and business to science and technology—Subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account. 

A ceasefire becomes ever more urgent in Gaza as Israel expands military operations and obstructs aid. As Donald Trump arrives in Saudi Arabia, the regional balance of power has shifted since his last term (9:55). Also on the show: introducing series two of “Boss Class”, on how to be a better manager (17:44). And we need your feedback! Please take our survey. Listen to what matters most, from global politics and business to science and technology—Subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

Tariffs against China were the centrepiece of Donald Trump’s “Liberation Day” trade plans. Our correspondent explains the significance of a new 90-day hiatus. Will Ukraine and Russia come to the negotiating table this week (7:51)? Why new techniques to compress the contrast between loud and quiet music could be damaging our hearing (15:35). And help us improve the show by taking this survey.  Listen to what matters most, from global politics and business to science and technology—Subscribe to Economist Podcasts+ For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.