What It Really Means to Regulate Your Nervous System—and How to Start

What if feeling better didn’t have to take months or years to figure out, but could start today? On this episode of The Dr. Hyman Show, I sit down with Dr. Scott Sherr to talk about why so many people feel stuck in what he calls a “sympathetic spiral of doom.” Energy is low, recovery isn’t what it used to be, and there’s a constant sense of stress that doesn’t seem to resolve. We walk through what’s actually happening beneath the surface, why it can be so hard to break out of that pattern once you’re in it, and how to start shifting your energy and recovery. Watch the full conversation on YouTube, or listen wherever you get your podcasts. In this episode, we discuss: • Why you feel “tired but wired” and what it actually means for your body • What’s keeping your energy low even when nothing obvious is wrong • How stress from your life and environment builds up and keeps you stuck • Why calming down doesn’t always work—and what to focus on instead • How to start rebuilding your energy so your body can recover and adapt We shouldn’t have to wait for something to go wrong to take action. The goal is to help your body function better so you can actually feel it day to day. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Perfect Amino, Korrus, Timeline, BON CHARGE, BIOptimizers and Pique. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. (0:00) Introduction and guest Dr. Scott Scherer (3:31) Understanding the sympathetic spiral of doom (5:06) Symptoms and signs of sympathetic overdrive (7:10) Sympathetic activation, mitochondrial function, and stress (10:02) Mitochondria: their role and impact in the body (12:31) Stress, metabolic dysfunction, and their effects (17:43) Nervous system, mitochondria, and the cell danger response (21:25) Survival, stress, and breaking the sympathetic spiral (23:11) Contributors to stress: top-down and bottom-up (25:56) Mitochondria, microbiome, and medication impacts (29:38) Mitochondrial dysfunction and mental health (32:19) Limitations of parasympathetic activation and addressing root causes (36:46) How mitochondrial stress leads to fight-or-flight (37:52) Steps to break the sympathetic spiral and support mitochondria (42:41) Methylene blue: benefits, uses, and safety (50:35) Methylene blue as an MAO inhibitor and for chronic infections (57:17) Case studies, third-party testing, and Transcriptions' evolution (1:02:36) Parasympathetic edge, recovery, and the GABA system (1:07:44) GABA, supplements, and interventions for stress (1:12:23) Addressing root causes and methylene blue usage (1:17:29) Transcriptions products, sleep formula, and practitioner ecosystem (1:19:49) OneBase Health, hyperbaric space, and final information

Longevity isn’t just about talent—it’s about what you’re willing to change when your body starts asking for something different. On this episode of The Dr. Hyman Show, I’m joined by Chris Paul—one of the most respected point guards of all time—to talk about the mindset that’s carried him through more than two decades in the NBA. We get into what shifted along the way and what it really takes to keep showing up at a high level year after year. Watch the full conversation on YouTube, or listen wherever you get your podcasts. Here’s what we cover: • Why what worked in your 20s stops working and what to do instead • How inflammation shows up and what improves when you address it • Why stress and poor sleep quietly drain energy and slow recovery • What simple habits actually move the needle over time • How understanding your data helps you make better daily decisions Your body is always giving you signals. The earlier you begin to listen and respond, the more it can support you over time. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Sunlighten, Korrus, Seed, Paleovalley, Pique and Made In Cookware. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Visit Korrus.com/DrHyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to paleovalley.com/hyman to save 15% off your first order today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Visit MadeInCookware.com and use code HYMAN10 for 10% off your order. (0:00) Chris Paul’s mindset, falling in love with monotony, and introduction by Dr. Mark Hyman (2:51) Chris Paul on hard work, success, and his grandfather’s influence (9:26) Longevity in the NBA, transition to plant-based diet, and dietary impact on performance (18:21) Effects of diet on performance, recovery, and family health habits (22:11) Impact of diet on athletic performance and Function Health insights (25:26) Emotional and family impact of health changes (27:52) Stress, gut health, cortisol, and the importance of rest (31:34) NBA players’ health insurance, short careers, and health education (34:52) Function Health’s accessibility and intelligence (37:32) Daily routines, hydration, and rest for athletes (45:06) Evolution of Chris Paul’s diet, recovery, and disconnecting from technology (48:24) The significance of sleep for athletes (52:42) Chris Paul’s nonprofit work and food access initiatives (55:00) Future plans, community, accountability, and health advice to a younger self

Seasonal allergies aren’t just about pollen—and if you’re only treating symptoms, you’re missing the real problem. What if your allergies are actually a sign that your immune system is out of balance? In this episode, we break down what’s really driving allergy symptoms and what you can do now to calm your immune system at the root. Here’s what you need to know before this allergy season gets worse: • Why allergies are a sign of immune dysfunction—not just a reaction to pollen • The hidden role of gut health, inflammation, and your microbiome in driving symptoms • Key nutrient deficiencies and environmental exposures that make allergies worse • A functional medicine approach to reducing symptoms naturally by restoring balance and not just blocking histamine You don’t have to suffer through allergy season every year. When you address the root causes, you can retrain your immune system, reduce your reactivity, and build long-term resilience. Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year. Join the 10-Day Detox to Reset Your Brain and Metabolic Health: https://drhyman.com/pages/10-day-detox Have a question you’d love answered on Office Hours? Submit it here.

Breast implants may have become increasingly common—but for some women, the experience doesn’t always unfold the way they expected. On this episode of The Dr. Hyman Show, I sit down with Dr. Jonathan Kanevsky, a board-certified plastic surgeon who made the decision to stop performing breast implant procedures after years of listening closely to his patients. We explore what he started seeing, how to approach this decision, and what alternatives are now available. Watch the full conversation on YouTube, or listen wherever you get your podcasts. You’ll learn: • How to tell if your symptoms may be connected to breast implants • What to consider before deciding to remove them • Why recovery after explant looks different for everyone • What safer, more natural alternatives are available today • How to support your body before and after surgery for better recovery This is a complex and deeply personal decision. My hope is that understanding the full picture helps you make a more informed one. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Maui Nui, Pique, Perfect Amino, BIOptimizers, Korrus and Made In Cookware. Go to mauinuivenison.com/hyman to claim your free 6-pack of their Wild Axis Venison Jerky Sticks. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Visit Korrus.com/DrHyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Visit MadeInCookware.com and use code HYMAN10 for 10% off your order. (0:00) Breast implants, health concerns, and medical profession perspectives (0:58) Introduction of Dr. Jonathan Kanevsky and personal stories (2:31) Correlation between breast implants, illness, and safety concerns (4:06) Breast implant-associated cancer, FDA warnings, and patient symptoms (6:29) Gaslighting in medicine and types of complications (8:02) Autoimmune reactions and explant surgery (13:15) Challenges and outcomes of explant surgery (16:57) Understanding toxins, metabolic, and cognitive effects of implants (18:36) The future of safe breast augmentation surgery (20:32) Introduction and history of fat grafting (23:14) Fat grafting techniques, results, and risks (28:50) New technologies in fat transfer and critique of new implants (33:10) Banking, growing, and sharing your own fat (36:27) Addressing ongoing concerns about implants’ health impacts (40:23) Surgery as ceremony: concept, history, and protocols (49:42) Post-surgery care, recovery, and dietary recommendations (55:10) Whole food, plant-based diets and nutritional interventions (57:29) Integrating alternative therapies and new surgical technologies (58:06) Where to find Dr. Jonathan Kanevsky and closing remarks (59:20) Disclaimer and final notes

Endometriosis affects 1 in 10 women yet it often takes years to diagnose, and many are told their pain is “normal” or simply treated with birth control or surgery. But endometriosis isn’t just a hormone issue—it’s a whole-body condition driven by inflammation, immune dysfunction, gut health, and environmental exposures. In this episode, we break down what’s really causing it and what you can do to address it at the root. I’m joined by my longtime colleague and friend, Dr. Elizabeth Boham, Medical Director and Functional Medicine Physician at The UltraWellness Center. Here’s what we break down: • Why endometriosis is not just a gynecologic condition and the root causes most doctors miss • The hidden role of gut health, inflammation, and the microbiome in driving symptoms • How estrogen imbalance and environmental toxins (xenoestrogens) fuel the condition • A functional medicine approach to reducing pain and preventing recurrence beyond medication or surgery If you’re struggling with endometriosis or unresolved symptoms and want a more personalized, root-cause approach, you can learn more about becoming a patient at The UltraWellness Center here: https://www.ultrawellnesscenter.com/becoming-a-patient/ Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year. Have a question you’d love answered on Office Hours? Submit it here   (0:00) Introduction, statistics, and overview of endometriosis and functional medicine (2:27) Introduction of Dr. Elizabeth Boham and explanation of endometriosis (6:10) The immune system, gut health, and their roles in endometriosis (10:29) The gut microbiome, estrogen metabolism, and the 5R approach (16:55) Xenoestrogens and detoxification strategies (22:53) Nutritional supplements and additional detox support (25:41) Surgery and lifestyle interventions for endometriosis management (30:20) Blood sugar, insulin resistance, and hormonal balance (32:11) Prevention and recurrence of endometriosis (33:40) Summary, key takeaways, and closing remarks (38:11) Sponsor: Gratitude to sponsors