Meet the Press NOW — May 25

The U.S. begins a blockade of Iranian ports after peace negotiations between the United States and Iran result in no deal to end the war. Pope Leo XIV says he has “no fear” speaking out against the Trump administration even as President Trump escalates his criticisms of the pontiff. Congressman Eric Swalwell (D-Calif.) drops out of the gubernatorial election after multiple accusations of sexual misconduct.

In his first-ever interview on American television, Cuban President Miguel Díaz-Canel tells Meet the Press that Cuba would fight back against any potential U.S. military action, saying Cuban leadership is prepared to “give our lives for the revolution.”

Kristen Welker speaks exclusively with Cuban President Miguel Díaz-Canel, Rep. Byron Donalds (R-Fla.) and Rep. Pramila Jayapal (D-Wash.) as Cuba faces pressure from the Trump administration for a change in leadership. Matt Gorman, Amna Nawaz, Steve Ricchetti and Julio Vaqueiro join the roundtable.

Pakistan's ambassador to the U.S. Rizwan Saeed Sheikh joins Meet the Press NOW as Vice President JD Vance travels to Pakistan for peace talks with Iran. NBC News correspondent Liz Kreutz walks through the return of NASA's Artemis II mission to Earth. NBC News senior reporter Jane Timm reports on President Trump's involvement in an Indiana Republican state Senate primary.

Ophir Falk, chief foreign policy adviser to Israeli Prime Minister Benjamin Netanyahu, discusses Israel’s strikes on Lebanon. World Central Kitchen Chef Aline Kamakian explains how she is feeding civilians on the ground of a war zone in Beirut. Cuban President Miguel Díaz-Canel tells Kristen Welker in an exclusive interview that he is not willing to step down even if the U.S. demands it. A Democratic focus group describe the party as “weak” and “floundering” ahead of the midterms.