Meet the Press NOW - May 21

Senate Republicans narrowly pass their version of the Trump agenda bill, with Vice President JD Vance casting the tiebreaker vote. President Trump visits the opening of a Florida immigration detention facility dubbed “Alligator Alcatraz” by Florida Republicans. Steve Kornacki analyzes the ranked choice vote in the New York City Democratic mayoral primary. The jury in the Sean “Diddy” Combs’ trial delivered a partial verdict on several counts.

The Senate considers amendments to the Trump agenda bill. Rep. Mike Turner (R-Ohio) discusses the fate of Trump's agenda and the situation in Iran as the IAEA Chief says the country could begin enriching more uranium in the coming months. Rep. Mary-Katherine Stone (D-Vt.) and Rep. Beau Baird (R-Ind.) discuss their work with engaging young people.

Sen. Markwayne Mullin (R-Okla.) and Sen. Chris Murphy (D-Conn.) discuss the Senate’s passage of President Trump’s tax bill. New York City mayoral candidate Zohran Mamdani talks about his victory in the Democratic primary.

President Trump calls the Supreme Court’s ruling limiting nationwide injunctions a “monumental decision.” Senate Republicans continue to work on President Trump’s One Big, Beautiful bill after the parliamentarian rejected their Medicaid provision. Rep. Jimmy Panetta (D-Calif.) discusses his takeaways from the Iran classified briefing.

Rep. Adam Smith (D-Wash.) discusses the intelligence shaping new congressional briefings on the U.S. strikes on Iran’s nuclear facilities. Rep. Tony Gonzales (R-Texas) reacts to the Senate parliamentarian rejecting key Medicaid cuts in President Trump’s tax and spending bill. NBC News’ Sahil Kapur, Vaughn Hillyard and Dan De Luce report on how the White House and Pentagon are managing conflicting reports on the destruction to Iran’s nuclear program.