Katherine Boyle on Shawn Ryan Image

Katherine Boyle on Shawn Ryan

30 August - 2 hours 51 mins
Podcast Series a16z Show

Venture capital has powered companies like Facebook and TikTok—but what if that same urgency fueled America’s defense and industrial base? Katherine Boyle, General Partner at Andreessen Horowitz and cofounder of the firm’s American Dynamism practice, argues this is the biggest business opportunity of our time.

In this conversation from The Shawn Ryan Show, Boyle discusses the rise of defense tech startups, why optimism drives her work, and how a new generation of engineers and founders is rethinking innovation and patriotism in America.

 

Timecodes: 

0:00 Introduction 

0:41 Patriotism, Optimism, and American Innovation

4:27 Startups vs. Legacy Primes in Defense

10:08 Venture Capital’s...

2 hours 51 mins

Series Episodes

The $3 Trillion AI Coding Opportunity

The $3 Trillion AI Coding Opportunity

Originally published on the a16z Infra podcast. We're resurfacing it here for our main feed audience. AI coding is already actively changing how software gets built. a16z Infra Partners Yoko Li and Guido Appenzeller break down how "agents with environments" are changing the dev loop; why repos and PRs may need new abstractions; and where ROI is showing up first. We also cover token economics for engineering teams, the emerging agent toolbox, and founder opportunities when you treat agents as users, not just tools.

37 mins

9 December Finished

The 80-Year Bet: Why Naveen Rao Is Rebuilding the Computer from Scratch

The 80-Year Bet: Why Naveen Rao Is Rebuilding the Computer from Scratch

Naveen Rao is cofounder and CEO of Unconventional AI, an AI chip startup building analog computing systems designed specifically for intelligence. Previously, Naveen led AI at Databricks and founded two successful companies: Mosaic (cloud computing) and Nervana (AI accelerators, acquired by Intel). In this episode, a16z’s Matt Bornstein sits down with Naveen at NeurIPS to discuss why 80 years of digital computing may be the wrong substrate for AI, how the brain runs on 20 watts while data centers consume 4% of the US energy grid, the physics of causality and what it might mean for AGI, and why now is the moment to take this unconventional bet.

30 mins

8 December Finished

What Comes After ChatGPT? The Mother of ImageNet Predicts The Future

What Comes After ChatGPT? The Mother of ImageNet Predicts The Future

Fei-Fei Li is a Stanford professor, co-director of Stanford Institute for Human-Centered Artificial Intelligence, and co-founder of World Labs. She created ImageNet, the dataset that sparked the deep learning revolution. Justin Johnson is her former PhD student, ex-professor at Michigan, ex-Meta researcher, and now co-founder of World Labs. Together, they just launched Marble—the first model that generates explorable 3D worlds from text or images. In this episode Fei-Fei and Justin explore why spatial intelligence is fundamentally different from language, what's missing from current world models (hint: physics), and the architectural insight that transformers are actually set models, not sequence models.

1 hour 1 min

5 December Finished

How AI Created the Fastest Product Cycle in History

How AI Created the Fastest Product Cycle in History

Recently, a16z General Partner Anish Acharya joined Ollie Forsyth on NEW ECONOMIES. They talked about why consumer tech is surging again, how AI is enabling 100M-user products at unprecedented speed, and what founders need to understand heading into 2026 — from distribution shifts to founder mindset to the mechanics behind the fastest product cycle in tech history.

50 mins

4 December Finished

Why AI Moats Still Matter (And How They've Changed)

Why AI Moats Still Matter (And How They've Changed)

a16z General Partners David Haber, Alex Rampell, and Erik Torenberg discuss why 19 out of 20 AI startups building the same thing will die - and why the survivor might charge $20,000 for what used to cost $20. They expose the "janitorial services paradox" (why the most boring software is most defensible), explain why OpenAI won't compete with your orthodontic clinic software despite having 800 million weekly users, and reveal how non-lawyers are building the most successful legal AI companies. Plus: the brutal truth about why momentum isn't a moat, but without it, you're already dead.

51 mins

3 December Finished

How To Lead | Ben Horowitz on My First Million

How To Lead | Ben Horowitz on My First Million

A16Z co-founder Ben Horowitz joins Shaan Puri and Sam Parr on My First Million to talk about how to be a great leader.

1 hour 10 mins

2 December Finished

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